U.S. Psychedelic Mushroom Industry

The U.S. psychedelic mushroom market size is expected to reach USD 4.32 billion by 2030, growing at a CAGR of 11.5% from 2025 to 2030, according to a new report by Grand View Research, Inc. The use of psychedelic mushrooms and other plant-based entheogens is gaining acceptance in the U.S., with a growing movement to decriminalize their use. Several cities and states have taken steps to legalize or decriminalize these substances, leading to a surge in interest and demand.

Psychedelic mushrooms have shown promising results in treating various mental health conditions such as depression, anxiety, PTSD, and addiction. As further research is conducted on their therapeutic potential, demand for these substances is likely to increase.

The primary application of psychedelic mushrooms is in the treatment of depression and anxiety disorders. Psilocybin, the active ingredient in these mushrooms, has been found to alleviate symptoms of depression and anxiety and even induce long-term positive changes in personality and behavior. This has sparked growing interest in the use of psilocybin as a potential treatment for other mental health conditions such as PTSD, addiction, and end-of-life anxiety in patients with terminal illnesses.

The growing awareness of mental health issues in the U.S. is a major factor driving the demand for psychedelic mushrooms. Traditional treatments for depression, anxiety, and other mental health conditions may not work for everyone, prompting many individuals to seek out alternative therapies, such as psychedelic therapy.

Moreover, there is an increasing interest in natural and plant-based remedies, as people become more aware of the potential risks and side effects of synthetic drugs. Psilocybin, the natural psychoactive compound found in psychedelic mushrooms, has been used for centuries by indigenous cultures for spiritual and therapeutic purposes. As the interest in natural and alternative therapies grows, the demand for psychedelic mushrooms is expected to continue increasing.

Psychedelic mushrooms also offer a potential treatment for cluster headaches, which are severe and often resistant to traditional treatments. Psilocybin has demonstrated effectiveness in reducing the frequency and severity of cluster headaches in some patients, offering new hope for individuals who suffer from this debilitating condition.

Gather more insights about the market drivers, restrains and growth of the U.S. Psychedelic Mushroom market

U.S. Psychedelic Mushroom Market Segments Highlights:

• The psilocybe product segment led the market in terms of revenue in 2024, owing to increasing research into their therapeutic potential and a growing trend towards natural and holistic health practices.
• The processed form segment is expected to grow at a CAGR of 12.2% over the forecast period, owing to easier to consume than dried mushrooms and more consistent dose of psilocybin.
• The de-addiction application segment is expected to grow at a CAGR of 12.3% from 2025 to 2030. As psilocybin, found in psychedelic mushrooms, is a potential treatment for substance abuse when paired with therapy.

U.S. Psychedelic Mushroom Market Report Segmentation

Grand View Research has segmented the U.S. psychedelic mushroom market based on product, form, and application:

U.S. Psychedelic Mushroom Product type Outlook (Revenue, USD Million, 2018 - 2030)

• Psilocybe
  • Psilocybe cubensis
  • Psilocybe semilanceata
  • Psilocybe azurescens
  • Psilocybe cyanescens
  • Psilocybe baeocystis
  • Others
• Gymnopilus
  • Spectabilis
  • Others
• Panaeolus

U.S. Psychedelic Mushroom Form Outlook (Revenue, USD Million, 2018 - 2030)

• Fresh/Whole
• Dried
• Processed

U.S. Psychedelic Mushroom Application Outlook (Revenue, USD Million, 2018 - 2030)

• Depression Relief
• Anxiety Relief
• De-addiction
• Recreational
• Others

Key U.S. Psychedelic Mushroom Company Insights

• Shroomland
• Galaxy Treats
• Blissmushrooms
• oneupmushroomsbar.com
• Psychedelic Mushy
• Psilocybin Lounge

Order a free sample PDF of the U.S. Psychedelic Mushroom Market Intelligence Study, published by Grand View Research.