North America OTC Hyaluronic Acid Industry

The North America OTC hyaluronic acid (HA) market is projected to reach USD 10.29 billion by 2030, growing at a CAGR of 7.9% over the forecast period, according to a report by Grand View Research, Inc. The market is being driven by shifting lifestyle habits, including rising obesity rates due to sedentary behaviors, increased fast-food consumption, and alcohol use—especially among the younger population.

Key Growth Drivers

1. Expanding Orthopedic Applications

Orthopedic use of HA is poised to become the most lucrative segment due to:

The aging population, particularly individuals over 60, who are increasingly affected by joint disorders such as osteoarthritis and rheumatoid arthritis.

Growing hospitalization rates due to arthritis, paired with greater awareness among healthcare providers of HA’s physicochemical properties.

An expanding portfolio of HA-based products designed to cater specifically to joint health and mobility support.

2. Rising Demand in Dermatology

HA’s role in stimulating collagen production and supporting skin structure is fueling its popularity in topical applications such as anti-wrinkle creams and serums.

Products leveraging HA are gaining traction due to their superior dermal penetration compared to alternatives like collagen.

The growing segment of women aged 20–65 years, especially those between 45–65 years (approximately 27% of the U.S. female population), are primary consumers of anti-aging and skincare products.

3. Increased Consumer Awareness

The OTC nature of HA supplements and skincare products has made them more accessible, while marketing efforts and rising awareness of HA’s benefits—such as improved hydration, elasticity, and joint lubrication—have expanded its appeal across demographics.

Market Challenges

Product saturation in topical skincare may increase competition.

Regulatory scrutiny of health claims made by OTC products may limit aggressive marketing.

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North America OTC Hyaluronic Acid Market Segments Highlights:

• By product, Dermatology segment accounted for the largest market revenue share in 2023. The rapid growth of this segment is being fueled by a surge in demand for HA-based fillers for various procedures, as well as a rise in cases of skin concerns such as wrinkles, acne, and scarring.
• Orthopedics is expected to register the fastest growth during the forecast period, driven by the rise of musculoskeletal disorders, sports injuries, and fractures.
• By sales channel, retail accounted for the largest market revenue share of 83.7% in 2023. Main factors that is anticipated to drive the market is the easy access to cosmetics and joint supplements in drug stores, departmental stores, and supermarkets.

North America OTC Hyaluronic Acid Market Report Segmentation

Grand View Research has segmented the North America OTC hyaluronic acid market report based on product, sales channel, and country:

North America OTC Hyaluronic Acid Product Outlook (Revenue, USD Million, 2018 - 2030)

• Dermatology
• Moisturizers
• Anti-wrinkle Crème
• Orthopedics

North America OTC Hyaluronic Acid Sales Channel Outlook (Revenue, USD Million, 2018 - 2030)

• Retail
• Online

North America OTC Hyaluronic Acid Regional Outlook (Revenue, USD Million, 2018 - 2030)

• North America
  • US
  • California
  • Texas
  • New York
  • Florida
  • Illinois
  • Other States
  • Canada
  • Mexico

Key North America OTC Hyaluronic Acid Company Insights

• Shiseido Company
• Lindberg Nutrition Products
• Nature’s Way
• Now Foods
• NeoCell Corporation
• Source Naturals, Inc.
• Doctor’s Best
• Derma E
• Earth Science

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