U.S. Peripheral Nerve Injuries Industry

The U.S. peripheral nerve injuries market size is estimated to reach USD 712.5 million by 2030, registering a compound annual growth rate (CAGR) of 7.4% from 2025 to 2030, according to a new report by Grand View Research, Inc. Several factors are contributing to the growth of this market, including rising healthcare expenditure across the country, an increasing prevalence of peripheral nerve injuries, an intensified focus on research and development initiatives, and a growing preference among patients for minimally invasive treatment procedures. These factors collectively are expected to continue driving the expansion of the market over the forecast period.

Technological advancements are playing a critical role in revolutionizing the treatment landscape for peripheral nerve injuries in the U.S. Innovative treatment options such as nerve grafts, nerve conduits, and neurostimulation devices have been developed, offering improved patient outcomes and aiding in faster recovery times. Moreover, the adoption of minimally invasive surgical techniques, such as end-to-end nerve sutures and nerve decompression procedures, is rising steadily among patients and healthcare providers. The popularity of these techniques can be attributed to benefits such as reduced recovery times, lower postoperative complications, and overall better patient satisfaction. These technological improvements are significantly contributing to the growth of the market by offering more efficient and less invasive treatment alternatives.

Further supporting the market growth are substantial investments by key players and collaborative efforts between academic institutions, industry participants, and healthcare organizations. These collaborations are fostering extensive research and development activities, leading to the discovery and commercialization of new treatment modalities for peripheral nerve injuries. For instance, in June 2022, Vascudyne, Inc., a prominent biotechnology company specializing in regenerative medicine, was awarded a grant from Regenerative Medicine Minnesota. The grant, totaling USD 100,000 for a one-year period beginning in June 2022, will fund a research project titled "Production of a Peripheral Nerve Wrap Using Tissue Tubes from Regenerative Engineering." The study aims to utilize Vascudyne’s proprietary TRUE Tissue technology, further advancing innovation in peripheral nerve injury treatments.

The COVID-19 pandemic has also had a notable impact on the peripheral nerve injuries market. The pandemic has accelerated the demand for minimally invasive procedures due to their advantages, which include shorter hospital stays, faster recovery periods, potentially lower overall healthcare costs, and compatibility with telemedicine services for follow-up care. These benefits have made minimally invasive treatments more appealing during and after the pandemic, thereby positively influencing the growth trajectory of the U.S. peripheral nerve injuries market.

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U.S. Peripheral Nerve Injuries Market Segments Highlights:

• Based on product/therapies, Nerve grafting segment dominated the U.S. peripheral nerve injury market share in 2024, accounting for 65.1%, owing to rapid advancements in nerve grafting techniques, such as autografts, allografts, and synthetic conduits
• Based on surgery, direct nerve repair segment dominated the U.S. peripheral nerve injury market and held the largest revenue share of nearly 42.5%. It is considered the gold standard of surgical treatment for severe cases
• Based on application, upper extremities segment held the largest U.S. peripheral nerve injury market share in 2024, accounting for 81.2%. increasing incidence of accidental falls and medical conditions, such as Guillain-Barre syndrome, diabetes, & carpal tunnel syndrome, is expected to drive the segment
• Based on end use, hospitals segment dominated the market in 2024. Increasing number of hospitals and surgical cases in hospitals are expected to boost the segment.

U.S. Peripheral Nerve Injuries Market Report Segmentation

Grand View Research has segmented the U.S. peripheral nerve injury market based on products/therapies, surgery, application, and end-use:

U.S. Peripheral Nerve Injuries Products/Therapies Outlook (Revenue, USD Million, 2018 - 2030)

• Nerve Grafting
  • Autograft
  • Allograft
  • Stem Cell Therapy
• Biomaterial
  • Nerve Conduit
  • Nerve Protector
  • Nerve Connector
  • Nerve Wraps

U.S. Peripheral Nerve Injuries Surgery Outlook (Revenue, USD Million, 2018 - 2030)

• Direct Nerve Repair
• Nerve Grafting
• Stem Cell Therapy
• Carpal Tunnel Release
• Internal Neurolysis
• Neurorrhaphy

U.S. Peripheral Nerve Injuries Surgery Outlook (Revenue, USD Million, 2018 - 2030)

• Upper Extremities
• Lower Extremities

U.S. Peripheral Nerve Injuries Surgery Outlook (Revenue, USD Million, 2018 - 2030)

• Hospitals
• Clinics
• Ambulatory Surgical Centers
• Others

Key U.S. Peripheral Nerve Injuries Company Insights

• Axogen Corporation.
• Stryker
• Regenity
• Integra LifeSciences Corporation.
• TOYOBO CO., LTD.
• Alafair Biosciences, Inc.
• SYNOVIS MICRO COMPANIES ALLIANCE, INC., (BAXTER INTERNATIONAL INC.)

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